Abstract

Validity of the Diagnostic Interview CRIDI -Autism Spectrum Disorders as a Gold Standard for the Assessment of Autism in Latinos and Mexicans

Author(s): Lilia Albores Gallo, Jose Juan Escoto Lopez, Gema Torres Suarez, Belen Carmona Ruiz, Marco Antonio Solis Bravo, Liliana Guadalupe Tapia Guillen, Tania Vargas Rizo, Emmanuel Sarmiento Hernandez, Gabriela Villareal-Valdes, Fernanda Rojas Miranda, Karla Castro Morales, Isis Suarez Ponce de Leon, Eunice Borrayo Magana, Alejandra Hernandez Duarte, America Catalan Nava, Ricardo Escudero Monteverde, Aymara Gatica Hernandez, Yassel Flores Rodriguez, Enrique Navarro Luna, Jorge Chavez Dozal, Marianela Moreno de Ibarra, Romina Aguerre Estevez, Javier Alonzo Alonzo, Sofia Arce Hernandez, Willian Gonzalez, Julian Moreno Granados, Lexma Guerra, Leidy Valencia Amado, Maria Constanza Peretto, Johanna Suarez Salazar

Objective

To validate the Criteria Diagnostic Interview (CRIDI-ASD/DSM-5), a cost-effective clinical assessment tool for the diagnosis of Autism Spectrum Disorders (ASD) in children and adolescents of Mexico, Latin America or Hispanics living in the US.

Method

The CRIDI-ASD/DSM-5 is a semi-structured observational interview based on the criteria of DSM-5. It consists of questions organized in the two dimensions: 1.- Deficits in social communication and interaction, 2.- Restricted and stereotyped patterns of behavior and interests and unusual sensory reactivity. We conducted an observational, validity study.

Results

The final sample consisted of 88 children seeking for a diagnosis of autism, or ADHD, between 18 months to 18 years of age. Participants were assessed with ADI-R, MINI-KID, K-SADS, VEANHi and CRIDI-ASD/DSM-5 Interview. Cronbach’s alpha for the total items was 0.91. Interrater reliability for the recorded interviews assessed by two different evaluators (N=40) ranged from ICC 0.74-.99 (M=0.86). Discriminant validity between ASD and ADHD was demonstrated through the t-Student test, showing significant higher mean raw scores for the ASD Group. Kappa coefficients between ASD diagnosis through ADI-R and/or K-SADS and/or Clinical Interview and the dichotomous result (ASD vs. no-ASD) of the CRIDI-ASD/DSM-5 Interview was k=0.82, with a Sensitivity of 92% and Specificity of 95%.

Conclusion

The CRIDI-ASD/DSM-5 is a valid, brief and cost-effective instrument for the diagnosis of ASD in Spanish-speaking children and adolescents.