Abstract

An overview of functional, structural and neurochemical imaging studies in individuals with a clinical high risk for psychosis

Author(s): Alice Egerton, Stefan J Borgwardt, Stefania Tognin, Oliver D Howes, Philip McGuire & Paul Allen

In recent years, a growing literature has emerged examining the neurobiological correlates of clinical high risk (CHR) for psychosis. Using a range of neuroimaging techniques, alterations in brain function, structure and chemistry have been reported in CHR subjects. In this article, we provide an overview of studies that have used MRI, PET and multimodal imaging to examine neurobiological abnormalities in CHR subjects.